Antibody Production after Partial Adrenalectomy in Guinea Pigs

Studies on the rapid production of Foot and Mouth disease hypenmmune antisera in guinea pigs

Effects of cortisone on experimental murine typhus. III. Effect of cortisone on the immune response in mice, rabbits, and guinea pigs.

Many attempts have been made to determine the effect of adrenal cortical hormones on immunization and immunity to various infectious and noninfectious agents. There are at least three questions to be considered in connection with the study of the immune response: first, the effect of cortical hormones on the development of antibodies, second, the effect these hormones may have on already formed...

A comparison of virulence of intraperitoneal infection of Burkholderia mallei strains in guinea-pigs

Male guinea pigs show high susceptibility to Burkholderia mallei and have been used as animal models in glanders studies. The purpose of our study was to elucidate glanders comparative pathogenesis in guinea pigs. We present here the histological changes and bacterial isolation that develop over time in guinea pigs inoculated intraperitoneally (IP) with two strain of B. mallei. Ten male guinea ...

Results of Acellular Dermis Matrix Graft Used for Tympanoplasty in Guinea Pig Model

Introduction: To describe the underlay tympanoplasty technique using an acellular dermal graft(AlloDerm) for tympanic membrane (TM) reconstruction in a guinea pig model and to demonstrate the feasibility of the technique using AlloDerm tissue harvested from the prepuce as a source of tissue for future grafting in human TM reconstruction.   Materials and Methods: The prepuce was divided during c...

Evaluation the Efficacy of Anthrax Vaccine against Challenge with a Highly Virulent Strain of Bacillus anthracis Isolated from Soil in Sheep, Goats and Guinea Pigs in Iran

  Protection of animals immunized against Bacillus anthracis is usually demonstrated by challenging with an appropriate dose of a strain of Bacillus anthracis that is lethal to unvaccinated animals inoculated at the same time. In this study the protective efficacy in anthrax vaccine (34F2 sterne strain spore) was evaluated in sheep, goats and guinea pigs challenged with subcutaneous inoculation...